Avalide is a combination drug that contains hydrochlorothiazide and Irbesartan. The former is angiotensin receptor blocker whereas the latter is diuretic drug. It has a biological half-life of 11 to 15 hours. The route of administration of this drug is oral.

What is Avalide used for?

Avalide medication would be prescribed for a longer period of time to treat high blood pressure. Hydrochlorothiazide prevents fluid retention. It helps the individuals by inhibiting the absorption of extreme salts in the body. This is achieved by flushing out the salts through urination.

Irbesartan avoids the blood vessels from diminishing thus increases the flow of blood to the heart. The generic and brand versions of a drug would be available in the market.

How to take Avalide?

The medication is taken by mouth with or without a meal. It is usually preferred a single dose daily. The patients get extreme urination while using this drug.

To avoid the disturbance while asleep, the dose can be taken three to four hours before sleep time. To avoid excessive water loss from the body, it is very important to drink plenty of water. Keep the body safe from dehydration as well as over hydration.

Taking Avalide medication on a regular basis can increase the success rate of treating the condition. Follow the dosage strength that is prescribed by the medico.

Never increase or decrease, double the dose or halt the medication without the advice of the healthcare provider. This would definitely not increase the effectiveness of the Avalide drug but might worsen the condition of the patient.

Some individuals may take pills for cholesterol, in this case take Avalide few hours before or after taking the cholesterol pill. Follow the instructions of the medico throughout the course duration.

Side effects

Some of the side effects that may occur during Avalide treatment are

  • Vision related problems,
  • shortness of breath,
  • dry mouth,
  • drowsiness,
  • restlessness,
  • stomach pain,
  • dizziness,
  • stuffy nose,
  • sore throat,
  • dry cough,
  • jaundice,
  • confusion,
  • headache,
  • weight gain,
  • increased heart rate .

These ill effects may or may not happen and it depends on an individual. If the patient suffers from any of these side effects or any abnormal change in the body condition, it is very important to seek medical assistance as soon as possible.

Interaction with other drugs

To get therapeutic effect on the body it is very important not to combine those drugs which might cause drug interactions. Few among those drugs are Lithium, birth control pills, cold medications, Lisinopril, Ibuprofen, Naproxen and Aliskiren.

Not only these but all those drugs that are purchased with prescription, without a prescription, herbal medications, dietary supplements as well as vitamin pill might cause interaction with the drug and leads to ill effects.


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