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Nitroglycerin is also known as Glyceryl Trinitrate and has a half-life of 3 minutes.

Medical Uses

Nitroglycerin is used in treating patients with chest pain as well as to treat high blood pressure during a surgery. Angina is a condition that occurs when there is an insufficiency of blood flow to the heart. When this drug is taken, it relaxes as well as widens the blood vessels thus enabling blood to flow easily to the heart. Hence the work load of the heart is reduced which in turn reduces the amount of oxygen needed by the organ. It does not offer total relief from pain, rather it just contains it.

Dosage and Administration

Nitroglycerin is available in different variants. They are oral, Topical, Transdermal, sublingual and Intravenous. In case of oral administration, the drug can be taken for three or four times in a day. The dosage strength required in an individual would be prescribed by the doctor after analyzing the health condition, response to the treatment as well as tolerance. So it would vary from person to person. It is important not to crush, break or chew it. The tablet should be swallowed as a whole in order to prevent the release of all the ingredients in the body at the same time. This would in turn prevent certain ill effects.

If Nitroglycerin Sublingual is prescribed for the patients, it should be kept under the tongue. Allow it to dissolve completely without chewing or breaking it. Burning as well as tingling sensation would be experienced when the pill starts to dissolve in the body.

Individuals using Nitroglycerin Topical can apply the cream on the skin twice a day. The ointment comes with a paper applicator which helps the patients to measure the correct dose. With the help of a paper applicator, the ointment can be applied without touching the medication with bare hands.

The medication comes as a patch which can be worn on the skin for 12 to 14 hours. In case of taking it as a Transdermal, patients can go to the clinic or hospital for getting injected.

Precautionary advice

  • Avoid drinking alcohol as it can alter the blood pressure in a harmful way and can also cause alcohol toxicity.
  • It is advised not to not take Nitroglycerin if you are allergic to its ingredients, pregnant, breast-feeding, have a history of heart ailments, low blood pressure, anemia, or dehydration.
  • Missing a dose is not advised, but if this happens do not double the dosage to make up for the missed dose.
  • Avoid venturing out into the heat or exercising as you may feel faint or light-headed.
  • Inform your doctor of any other drugs being taken to prevent harmful interactions.
  • Do not drive or do anything that requires your complete focus and attention.

Side Effects

Some of the common side effects are burning, itching, bloating, trouble breathing, head ache, excessive weight gain, sweating, feeling hot, dizziness, light headed, swelling in the face, legs or arms, tightening in the chest, numbness and tingling of the hands or feet. Few among the rare symptoms are sore throat, bleeding, abnormal heart rate, fever, dark colored urine, pale skin, fainting, confusion, and scaly skin. Seek medical help in case of extreme side effects.

What drugs interact with Nitroglycerin?

Drugs like dietary supplements, vitamins, minerals as well as those bought with prescription and over-the-counter may interact with this medication.

Lozol is an antihypertensive medication and is a diuretic. The diuretic constituents are polar sulfamoyl chlorobenzamide moiety and lipid soluble methylindoline moiety. The medicine also comprises of microcrystalline cellulose, hypromellose, magnesium stearate, lactose, corn starch, coloring agent, pregelatinised starch, talc and polyethylene glycol.

Medical Uses

Lozol is used in the treatment of high blood pressure and also to treat salt and water retention known as edema that could be as a result of congestive heart failure. The pill works by making the kidneys to dispel large quantity of water and salt. When there is reduced blood pressure, kidney problems, strokes and heart attacks can be averted. Minimizing the amount of salt and fluid in the body can help to reduce the swelling and breathing problems and can enhance the body’s ability to exercise.

Dosage and Administration

As Lozol is indicated for oral administration, it can be taken by mouth once each day with or without food. The pill can increase amount of urine or make a person to urinate frequently. Hence to alleviate these problems, it is best to take the pill before 6 pm so as to not get disturbed due to urination while asleep.

The standard starting dose of Lozol for high blood pressure is 1.25 mg and the standard recommended dose for fluid retention is 2.5 mg. Your physician might however increase the dosage to 5 mg depending upon you condition.

Take the doses of Lozol regularly and at the same time every day so as to help you remember better. This drug should not be got into children’s hands and elderly people will have to take a lower dosage of the pill.

Side Effects

Common side effects of the medication include dehydration, hypokalemia that could lead to abnormal cardiac rhythms. Patients can develop muscle weakness due to hypokalemia. One could also suffer from hypomagnesaemia where the blood magnesium content is too low. Other crucial changes in the body can be lowered blood pressure, changes in vision, headache, dizziness, light headedness, increased cholesterol, nervousness, impotence, irritation, fatigue.

Precautionary advice

The foremost thing to do is reveal the record of medical ailments you are already suffered, the medications taken for that and if presently you are traumatized by any disease. Patients who are undergoing problems related to the nervous system should be very cautious prior to taking this medication. Refrain from getting more exposed to the sun as this drug can change your body condition wherein it becomes more sensitive to sun rays. There can be circumstances where you need to undergo a surgery and it is critical to tell the medical professionals involved that you are presently taking Lozol.

Tell your physician if you are allergic to Lozol or if you have any other allergies. As this medicine consists of certain inactive ingredients, it can cause some allergic reactions in some patients. Talk to your health care professional if you suffer from some medical condition like kidney disease, liver disease, gout disease, diabetes or if you had nerve surgeries. Consuming alcohol with this drug can cause sedative effects.

Belonging to a class of potassium-sparing diuretics (water medication) Aldactone is a prescription medication that is approved by FDA. It is a steroid that works by blocking mineralocorticoid receptors (drugs that are used as adjunctive therapy). The drug also blocks androgen and progesterone. People with kidney disease or high level of potassium in blood are not supposed to take this medication. Because of its high prominence, the medication was found in the World Health organization’s list of Essential medicines that is needed for basic health system.

Medical Uses

Aldactone is majorly used in the treatment of heart failure, high Blood Pressure, hypokalemia (low potassium levels), acne in women and hormone replacement therapy for transwomen. When it is used as a combination drug, it is used in the treatment of early puberty and a neuromuscular disease, myasthenia gravis. This medicine is prescribed for use in women who notice hyperandrogenism (androgen excess), which is a symptom of polycystic ovary syndrome. Lower dosage or topical form of this med is prescribed for men and women with androgenic alopecia. The medication is also utilized to prevent strokes, kidney problems and heart attacks.

Dosage and Administration

Aldactone comes in the form of tablet that has to be consumed with water. If the person experiences upset stomach he can try taking the medicine with milk or food. As it causes frequent urination, an individual taking this medication can take it earlier to avoid urinating at bed times.  The medication is available in dosage ranging from 25mg to 100mg.

When it is taken for the treatment of hypokalemia, depending on the medical condition and age of the person he is prescribed with any of the mentioned dosage. But when the medication is prescribed for heart failure patients, 25mg of Aldactone is prescribed which may be changed depending on the tolerance of the person to the medication.

Side Effects

The side effects that arise while taking Aldactone are frequent urination, dry skin, rashes, ataxia (lack of control of normal movements performed by body), erectile dysfunction, irregularity in menstrual periods and vomiting. As the medicine reduces the androgen level, it can cause gynecomastia (enlarged breast tissue), breast tenderness and physical feminization in men. Side effects like renal failure, hyperkalemia (increased concentration of electrolyte potassium in the blood) which can be life threatening may also be caused by this medication.


This medication might interact with non-steroidal anti-inflammatory drugs, steroids like prednisone and skeletal muscle relaxers. But these are not the only type of drug interactions that are identified as other might also occur.

Plavix is the brand name of the drug Clopidrogel and it works as an antiplatelet agent. It is an important medication that has many uses as it can regulate clotting problems in the blood. The medication is highly potent and it can be taken safely only with a valid doctor’s prescription.


Plavix is used for preventing platelets from sticking to one another and causing blood clot. It is also used for preventing other problems related to blood vessels such as high Blood Pressure in those who recently had a stroke or heart attack.

Dosage and Administration

Plavix is available for use as film-coated compressed tablets that are in the dosage strengths of 75 mg and 300 mg. The 300 mg is considered in many treatments as a loading dose, following which the individual may take the 75 mg dose on a once daily basis or as decided by the healthcare provider.

Follow the instructions provider by the doctor regarding the administration of Plavix. It may be taken either with or without food. Do not modify the dosage by increasing or decreasing without the consent of your doctor as it would not be suitable for your health. Discontinuing taking the drug abruptly can also affect your health. Higher doses would only increase the risk of side effects. Do not compare your symptoms and improvement with other patients who have the same problem. Do not stop taking Plavix without checking with your physician even if you feel normal.

Precautionary advice

Follow the safety precautions mentioned below while using the medication.

  • Since the drug can cause you to bleed easily, avoid involving yourself in activities that can cause cuts or injuries easily.
  • Do not take Plavix along with Aspirin.
  • Drinking alcohol while taking this drug can increase the risk of stomach bleeding.
  • Pregnant and breast-feeding women should not take this medication as it can produce harmful effects on the baby.
  • Ensure that you are not allergic to any of the ingredients before taking the pills.
  • The drug is not recommended for use in children below twelve years of age and elders who are above sixty.

You should not consume Plavix if you have any medical condition related to bleeding, brain, stomach, kidney and others. It is also not advisable for pregnant women and lactating mothers to take this medicine without prescription.

It is crucial to read those details before you start using the drug. For instance, using the medication would increase your bleeding when you are injured. Thus, you need to very careful while using sharp items and heavy objects. Drinking alcohol while using the medication will also induce bleeding inside stomach

Side effects

Adverse effects experienced with the use of Plavix should be treated immediately, particularly if they are severe or persistent. These may be:

  • Bleeding in the nose
  • Bleeding that doesn’t stop
  • Signs of internal bleeding like tarry or bloody stool, and coughing up blood
  • Weakness
  • Fever
  • Pale skin
  • Easy bruising
  • Heart attack symptoms like chest pain, nausea, sweating, pain that spreads between the arm and the jaw
  • Stroke symptoms like sudden numbness, headache, slurred speech, trouble with balance or vision

Trandane is a prescription medicine which belongs to a group of nonselective beta and alpha adrenergic antagonist. It is manufactured by Prometheus laboratories and was approved by FDA in the year 1984.

The medicine is injected into the vein in case of severe hypertensive situations. It is also available for oral administration in the treatment of hyper tension for a long term. But only small dose of this pill is prescribed because when given in high doses it causes steady drop in blood pressure when the suddenly person stands.

Taking Trandane is effective only when the person takes a proper hygienic diet and maintains his weight alongside by doing exercises.

What is Trandane used for?

Trandane is mainly used in the treatment of malignant hypertension, which is characterized by hypertension with minor impairment of central nervous and cardiovascular system.

The pill is also utilized in the treatment of postoperative hypertension and rebound hypertension (long term medical condition where blood pressure in the arteries is intently elevated) resulted from beta blocker withdrawal.

In particular, Trandane can be used in the treatment of pregnancy induced hypertension that is combined with pre-eclampsia (disorder of pregnancy indicated by high blood pressure and large quantity of protein in urine).

How to take Trandane?

Trandane is available in 100, 200 and 300mg formulations and it can be taken with or without food. Initially 100mg of this pill is prescribed to be taken twice a day. The person can consult a doctor and increase the dosage if no difference has been witnessed in 3 days.

Similarly when it is injected intravenously, 20mg is injected at first which is accompanied by 40 mg every 10minutes to make a total dose of 300mg a day. Trandane medicine should be taken in the way it has been prescribed. An individual should seek medical help if the drug is overdosed.

Side effects of Trandane

Some of the Common side effects that occur in the initial stage of consuming the pill are

  • light headedness,
  • nausea,
  • dyspepsia,
  • nasal congestion,
  • fatigue.

The adverse side effects are

  • sudden change in weight,
  • chest pain,
  • slow heart rate,
  • swelling of lower legs.

If you experience the above mentioned serious side effects then it should be treated by a physician immediately.

Interactions with other drugs

Trandane should not be taken with antidepressants like amitriptyline, imipramine as they will worsen the condition. Also it should not be taken with drugs that are used in the treatment of asthma.

Any drug that is taken by the patient should be informed to the doctor before starting his treatment with this drug.

Triamterene is a diuretic, which is available as the generic formulation of Dyrenium. The route of administration of this drug is by mouth. The protein binding in this tablet is 67 % and has a half-life of one to two hours.

What is Triamterene prescribed for?

Triamterene is used in preventing the body from absorbing excessive salts as well as maintaining the level of potassium mainly caused by complications such as high blood pressure (hypertension). This is achieved by increasing the urination thus making the body to get rid of excessive salt as well as water. This in turn helps the kidney to get rid of excessive potassium and maintain the level of it.

Triamterene is also used in treating edema, nephrotic syndrome, cirrhosis of liver, as well as congestive heart failure. When the excessive water is reduced from the body, it in turn reduces fluid in the lungs and helps the patient to breathe easily.

Triamterene is often prescribed in combination with hydrochlorothiazide.

The efficacy of Triamterene in lessening the swelling of arms, abdomen or legs is also good.

Dosage and Administration

Triamterene medication is available in the dosage strengths of 50 mg and 100 mg. You have to consult with a health care professional and decide which dosage strength would be suitable for your medical condition. A doctor would instruct you to commence with smaller dosage strength then increase over a period of time.

Triamterene can be taken by mouth with a meal, as prescribed by the medical practitioner to prevent nausea or stomach upset. The pill is taken once or twice a day depending upon an individual’s illness.

To avoid urination during sleep, don not take Triamterene few hours before going to bed. Just like other pills, the dosage strength depends on the tolerance, response to the treatment as well as the severity of the problem.

In case of edema, the dose of Triamterene should not exceed 300 mg per day. When the patient is taking this pill to treat high blood pressure, the dose should not exceed 100 mg in a day.

As Triamterene would increase the level of potassium in the body, avoid taking potassium rich foods in a meal or any potassium tablets. It is essential not to stop the course of therapy abruptly as this would not only cause withdrawal of symptoms but also leads to ill effects. Consult the doctor and follow the instructions throughout the healing process.

Side effects of Triamterene

Numbness, weakness, breathing troubles, abnormal heart rate, confusion, tremors, restlessness, dizziness, light headed, nausea, loss of appetite, jaundice, head ache, dry mouth, vomiting and fever are some of the side effects that may be caused while using Triamterene.

Interaction with other drugs

There are certain drugs that could interact with Triamterene. Insulin or diabetes medicines, Lisinopril, Ramipril, Lithium, ACE inhibitors, Indomethacin, Aspirin, Diclofenac, Naproxen, Nabumetone, Etodolac and Piroxicam are a few among them.

They are chances for the ingredients in the drug to trigger allergy symptoms in you. Tell about the medications to the physician especially those bought with prescription, over-the-counter, herbal products as well as vitamin medications to your doctor in order to avoid interaction with Triamterene.

Doxazosin which is also available under the brand name Cardura is an alpha 1-andrenergic receptor blocker. The drug works by relaxing the muscle of vascular cells, thereby decreasing the Blood Pressureand may even produce sedative effects.

Doxazosin comes in dosage strengths of 1 mg, 2 mg, 4 mg and 8 mg. The prescribing doctor may begin the patient on the minimum dose first and gradually increase the strength based on the response to treatment. The biological half-life of the medication is about twenty-two hours.

Medical Uses

The drug’s properties make it an effective treatment for high blood pressure (hypertension) and enlarged prostate or benign prostatic hyperplasia (BPH). The compressed pills may also be used for treatment in patients diagnosed with erectile dysfunction and chronic epididymitis.

Before taking Doxazosin, the patient should be aware of certain health conditions that may affect the efficacy of the blood pressure medicine. People who have conditions like constipation, liver problems, low blood pressure, and any blockages in the digestive tract are not advised to take this drug.

Dosing Guide

One should also read up the instructions for use on the product label to ensure that the drug is taken correctly. After the initial dosage, there may be symptoms of dizziness or fainting due to the strength of the drug and the first response to treatment. Since high blood pressure does not show any symptoms easily, the drug may be prescribed for long-term use with the dose increased or decreased accordingly.

Precautionary Advice

One should regularly check the blood pressure or prostate condition while on this drug therapy. The drug should never be discontinued or restarted without the healthcare provider’s knowledge and consent. While taking Doxazosin, one should avoid standing up suddenly or standing too long as the individual will be prone to feeling vertigo or dizziness. Nursing women should seek the advice of a medical practitioner before taking this drug as the active ingredient can pass through breast milk.

Side Effects

Usage of Doxazosin can cause side effects like tiredness, headache, dizziness, drowsiness, and low blood pressure. These symptoms go away in a few weeks but when they are more severe and persistent, seek emergency medical attention. One should also be aware and get immediate help for the adverse effects of light-headedness, chest pain, trouble breathing, stomach bloating or pain, erection lasting for four hours or longer and painful erection.

What drugs interact with Doxazosin?

Drugs that the patient should disclose to the healthcare provider to avoid any harmful interactions with this medication are HIV medications, erectile dysfunction pills, antibiotics, antidepressants, and other blood pressure medicines. This medication can also affect the pupil during a cataract surgery and hence the doctor must be informed when taking the drug. Other OTC drugs, vitamins and herbal supplements can also interact harmfully and should be disclosed to the physician.

Digoxin is made from the leaves of the plant called as digitalis lanata. This drug is the generic formulation of Lanoxin. The half-life of the pill is about 36 to 48 hours. The route of administration is oral as well as intravenous.

Medical Uses

Digoxin is used in treating conditions like atrial fibrillation, abnormal heart rate, as well as heart failure. When the condition is treated, it helps the patient to provoke the ability to walk, or do any exercise as well as strengthens the heart. Certain risks like blood clots, heart attack and stroke can be reduced when an individual takes medication for irregular heart rate. The working mechanism of the drug is that, it affects minerals like sodium or potassium which is present inside heart cells. This reduces the strain that happens in the heart and helps a patient to achieve a normal and a steady heart rate.

Dosing guide

Digoxin is available as both tablet and injectable forms. The dosage strengths of compressed tablets are 0.125 mg, 0.25 mg, and 0.50 mg. The individual dosages are prescribed by the healthcare provider based on the age and weight of the patient, apart from the condition being treated.

Liquid form of this drug is also available in the market. It is essential to measure the liquid form of this drug with a dose-measuring spoon. Never use a household spoon for measuring the dose. The blood test as well as kidney function tests should be done at regular intervals while taking this drug.

Do not stop taking Digoxin suddenly to prevent side effects as well as withdrawal of symptoms. Only the drug which is formulated in an authentic way provides a therapeutic effect on the body.

Side effects

Vomiting, loss of appetite, nausea, bloody or tarry stools, blurred vision, unusual behavior, hallucinations, enlarged breasts in men, depression and weakness are a few side effects that may be caused by Digoxin. To avoid any effects to the patients, it is wise to consult with the medical practitioner regarding certain medical ailments. Heart conditions like “AV block”, heart attack, Wolff-Parkinson-White Syndrome, thyroid disorder, kidney disease, and electrolyte imbalance are some among them.

Precautionary advice

Digoxin should be consumed only after consulting with the doctor and getting the correct dosage prescribed for you. Any drug allergies and medical history would affect the way this medication works in the body. Inform the doctor regarding such allergies, recent incidence of heart attack, kidney problems, thyroid disorder, any other heart conditions, and if you have an electrolyte imbalance. Pregnant and breast-feeding are advised not to take this drug unless it is the only option. Children with heart conditions who are administered with this drug should be carefully monitored for any complications.

Taking certain drugs together would affect the way Digoxin works. It could worsen the health condition of the patient. Hence it is important not to take those drugs together. Drugs that are diuretics and steroids can interact adversely if taken with Digoxin. Azole antifungals, Amiodarone, Lapatinib, Macrolide antibiotics, Rifampin, Dronedarone, and Propafenone are a few medications that may cause interaction.

Torsemide belongs to a class of medications called diuretics and hence is known as a water pill which makes a person to excrete more urine. This is a prescription drug which is available in the brand form with name Demadex.

Torsemide was approved by the Food and Drugs administration in the year1993. This med is available in the form of tablets and can be taken upon doctor’s recommendation.

Medical Uses

Torsemide is used to treat the excess fluid in the body that could be caused due to various medical conditions like liver disease, kidney disease or due to failure of the heart. It is also used to treat high blood pressure along with other medicines.

Torsemide works by allowing the kidney to excrete excess amounts of electrolytes especially the sodium and potassium salts and extra fluid in the body known as edema including water. This can minimize certain symptoms like shortness of breath and swelling in the arms, legs and abdomen.

Dosage and Administration

Torsemide can be taken by mouth as it is insisted for oral administration while having food or without food.

Do not take Torsemide within four hours to your bed time so as to prevent oneself from urinating frequently or can be taken before 6 pm.

The dosage of Torsemide depends upon individual’s age and response to the medication. The dosage however should not be increased or decreased or taken more than recommended time period.

Do not take two doses of Torsemide at once. The standard recommended dose for fluid retention ranges from 5-20 mg. The ideal dosage for high blood pressure is 5 mg.

Precautionary advice

  • Torsemide medication is not safe for patients who have experienced kidney failures, liver problems or gout.
  • People who are not able to urinate or suffer from any urinary complications should not take Torsemide.
  • Usage of Torsemide would lower the potassium level in the body. So, you have to take potassium rich foods or supplements to compensate it.
  • Consulting a doctor is a must if you are pregnant, nursing a baby or attempting to become pregnant.
  • Torsemide would change the blood sugar level in the especially for diabetes patients. So, ask your doctor on how to take this drug safely along with diabetes medication.

Side effects

People may experience frequent urination, cough, and ringing sound in the ears, cough, headache, excessive thirst and weakness while on Torsemide. One could also suffer from orthostatic hypotension where the drug causes low blood pressure and the person feels dizzy and lightheaded.

Certain severe side effects of Torsemide comprises of chest pain, gastrointestinal bleeding, dehydration, fainting, rectal bleeding, allergic reactions, skin reactions, decrease in white blood cells and platelets.

Interactions with other drugs

Govern the amount of sodium and potassium intake while taking Torsemide and adopt suitable changes in your diet.

Torsemide could interact with other herbs or vitamins you might be taking. Using alcohol can increase the risk of low blood pressure.

Talk to your doctor if you wanted to take alcohol with Torsemide. Inform your physician if you are taking any other medical course or if you are allergic to the ingredients of this pill so as to safely prevent drug interactions.

Dipyridamole is a coronary vasodilator and belongs to a class of drugs known as platelet inhibitors. It is a yellowish crystalline powder that is easily soluble in methanol, alcohol and slightly soluble in water. The tablet also comprises of inactive components like hypromellose, polyethylene glycol, iron oxide yellow, corn starch, povidone, magnesium stearate, titanium dioxide and lactose monohydrate. This tablet is not available in the brand formulation.

Medical Uses

Dipyridamole is used in combination with blood thinners like warfarin in order to prevent the formation of clots when a heart valve replacement is being performed. The pill can assist in the continuous flow of blood by hindering the platelets to group together thereby keeping the blood vessels of the heart open. The drug can also be used to minimize the risk of strokes in patients who have the risk of developing clots. This tablet can extend the abnormally reduced survival time of the platelet in a systematic manner.

Dosing guide

Dipyridamole is available in the form of tablets and each tablet formulation comes in the dosage strengths of 25 mg, 50 mg and 75 mg. This drug can be taken by mouth usually four times each day.

The dosage of Dipyridamole differs for every individual and is based on the patient’s age, medical condition and his/ her response to the drug. To get the best results from the drug, take the medicine at the same time each day so as to help you remember better. Never take the drug in higher or lower dosage or in more or less numbers as this could cause severe health complications.

Use Dipyridamole exactly as prescribed by the doctor and clear all your queries related to the drug. Read the prescription label thoroughly before beginning the medical course.

Side Effects

Certain common signs of allergic reactions include diarrhea, vomiting, headache, rash, stomach ache and itching. Other unusual side effects can be bruises or bleeding that is unusual, pain in the chest, skin or eyes getting yellowish, dark urine, confusion, stammering or fainting.

Precautionary advice

  • Avoid taking Dipyridamole along with Aspirin or any other similar painkillers. Even if you are taking any over the counter pills, vitamins, or herbal supplements, ensure that you inform your doctor so as to avoid any harmful interactions and increased side effects.
  • Also disclose your complete medical history with your healthcare provider, especially if you have conditions like heart disease, chest pain, asthma, irregular heartbeat and muscle weakness.
  • Dipyridamole can be made safe for use by also informing the physician if you are nursing a baby, currently pregnant, become pregnant while taking the drug, or expect to become pregnant.
  • Overdose of Dipyridamole can result in severe chemical reaction. Let your doctor know if you are taking any other prescription medication, over the counter pills or any other herbal supplements in order to enable the doctor process the right medication for you in the ideal dosage strength thus preventing any allergic reactions and drug interactions.

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