Cordarone is the trade-name for the generic formulation amiodarone and it is used for treating irregular heartbeat conditions.

Cordarone was discovered in the year 1961 and is identified as the most important medications in the basic health care system. It is also sold under other brand-names such as Paceron and Nexterone.

Medical Uses

Categorized as a class III antiarrhythmic agent, Cordarone is very effective in treating multiple types of cardiac dysrhythmias or arrhythmia. This is a condition where the heart beat is irregular in the sense that it is either too slow or too fast. Such irregularities occurring on a severe or unmanageable level can only be treated by antiarrhythmic agents like amiodarone.

Cordarone is only used in emergency cases when the heart disorder becomes life-threatening.

Dosage and Administration

Cordarone is available primarily in the tablet form at the dosage strength of 200 mg. This pill is scored on one side and has ‘200’ imprinted on the other side. The drug may be split and then used if required. Multiple doses may be taken in a day depending on the severity of the condition.

Cordarone comes in the form of a tablet and an injection, but the initial dose must only be taken under doctor’s supervision as this enables the doctor to monitor the heart condition of the patient and the patient’s response to the treatment.

The initial dose of Cordarone must only be taken in a hospital setting. Aside from this condition the medication is also used in the treatment of ventricular fibrillation, a heart problem that is defined as erratic electrical impulses and rapid heartbeats.

Consequent doses of Cordarone can be taken by the patient himself but by strictly adhering to the instructions provided by the doctor. It can be taken either with or without food.

Cordarone needs to be taken in the same form each and every time meaning, one should not shift between the tablet and injection. Frequent medical tests are in order, as amiodarone has long lasting effects on the body. Any effect on the eye, liver or any other function of the body must be checked and rectified immediately.

Precautionary advice

Cordarone can increase the toxicity level in a person and hence it is prescribed for use only when there is no other option when other drugs have not worked. Potency of Cordarone is very high and due to the condition being treated the patient should opt to stay in a hospital during the initial week of the drug course. It is possible, though rare, that the drug can worsen the arrhythmia condition.

Cordarone can increase photosensitivity which would require protection from sunlight. Inform the healthcare provider of your complete medical history and also any drugs being currently taken to avoid potentially dangerous interactions.

Side Effects

Some side effects that occur with Cordarone are classified as less severe while other are classified as severe side effects that need to be reported immediately. Less severe side effects include:

  • Tremors
  • Abnormal functioning of the liver
  • Feeling restless or weak
  • Vision problems
  • Appearance of hollows around lights
  • Constipation


Severe side effects of Cordarone for which the doctor should be contacted are:

  • Overactive or underactive thyroid – Look for symptoms such as stomach pain or weight loss
  • Blurred vision
  • Respiratory problems
  • Worsening of the heartbeat pattern
  • Lightheadedness

What drugs interact with Cordarone?

There are many drugs that interact with the functioning of Cordarone. Tell your doctor about all the medication that you take and especially about if you are taking the ones in below list.

  • HIV/AIDS medication
  • Blood thinner like Jantoven, warfarin and Coumadin
  • Antibiotic medications
  • Cancer medications
  • Medications that cure mental illnesses
  • Antidepressants
  • Water pill or diuretic
  • Blood pressure medications

A doctor can inform you about all these drug interactions when you approach him/her to get a prescription.


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