This is a transdermal skin patch antidepressant. Emsam consists of the active component selegiline that prevents the breaking down of chemicals in the brain that is often imbalanced in people who are affected by Depression. When it is applied to unscathed skin, it delivers selegiline for over a 24 hour period.

Drug Data

The base of selegiline is colorless to yellow liquid. It is a matrix type transdermal system consisting of three layers. The first layer is the backing fill, the second layer is the adhesive drug layer and the third layer consists of release liners that are discarded later after use.

The patches comprises of inactive ingredients like acrylic adhesive, polyethylene, polyester, polyurethane, ethylene vinyl acetate and silicon coated polyester.

Emsam is predominantly used in the treatment of major depressive disorder in adults. It works by restoring the balance of certain natural chemicals in the brain known as neurotransmitters. The drug elevates your mood and feelings. This drug is a patch for use only on the skin.

Emsam pill is a member of large class of antidepressants called monoamine oxidase inhibitors or MAOI’s which aren’t in use anymore but can be beneficial for people who do not respond to other types of antidepressants. As it is used as a patch over the skin, it avoids in getting contact with the stomach.


Apply the Emsam patch to clean, dry and hairless skin and press it firmly. The patch can be applied on certain places of the body like chest, thigh, back or outer part of the upper arm.

The patch can be left untouched for over 24 hours and can be replaced with a new one. It can be left on even while being in water for swimming or bathing.

The next Emsam patch should not be placed on the same place, it should be applied on a different place. One should not wear more than one patch at the same time and should wash the hands thoroughly after using them.

Do not get the patch exposed to sunlight and in case of surgery, inform your physician ahead.

Side effects

The Emsam can cause some uneasiness in the body like,

  • drowsiness,
  • weakness,
  • tiredness,
  • dizziness,
  • irritation over the area of application,
  • sleeping problems,
  • constipation,
  • dry mouth.

Serious side effects include,

  • fainting,
  • muscle stiffness,
  • changes in sexual interest,
  • severe stomach pain,
  • Rarely the drug can also cause high Blood Pressure.

Relative Contraindications

Emsam can easily interact when other drugs are taken along with it. Any other anti-depressant, cold medicine that consists a decongestant, prescription or over the counter pills can all affect when taken simultaneously and can result in drug interactions.


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