Medrol is the trade name of Methylprednisolone and belongs to a class of drugs called as Corticosteroids. It is a white crystalline, odorless tablet. It has a biological half-life of 18 to 26 hours. It is an alternative of Prednisolone and methylated at carbon 6 of the B ring.

Medical Uses

Medrol is taken to treat certain conditions like arthritis, severe allergic reactions, blood disorders, certain type of cancer, eye problems, skin disorder, lung, kidney or intestinal problem and immune system disorders. This Corticosteroid Medication is developed to imitate the actions that are done by natural Corticosteroid hormones in the body. This helps to relieve symptoms such as allergic reactions, inflammation and swelling pain.

Dosage and Administration

Medrol is available in the dosage strengths of 2 mg, 4 mg, 8 mg, 16 mg and 32 mg. Each of these dosages comprise of equal amount of methylprednisolone in them. They also have calcium stearate, corn starch, lactose, mineral oil, sorbic acid and sucrose in common along with erythrosine sodium for the 2 mg dosage.

Medrol should be taken by mouth along with milk or food. Dosing schedule differs in the treatment. The doctor would prescribe the patient to take pills every day or to take the drug once in two days. This depends on the medical condition as well as the response towards the first pill. It is very important to consult the doctor before starting the healing procedure. Halting the treatment, increasing or decreasing the doses all of a sudden would lead to withdrawal symptoms. Hence patients should avoid such things without doctor’s advice.

Before taking medrol, discuss with the physician regarding certain medical ailments like heart related diseases, liver or kidney problems, seizures, thyroid, mental disorders, HIV, TB, herpes and recent vaccinations.

Precautionary Advice

When you are on a course of treatment with Medrol, you should not breastfeed. In case you get pregnant while on the medication, do inform about the same to your doctor immediately.

Do not come in contact with people having cold and infection as the drug has the ability to affect your immune system that can hamper your capability to battle illness. As this medication can cause loss of calcium and subsequently can lead to the development of osteoporosis, you have to take adequate calcium and potassium supplements. Keep a watch on the level of your blood sugar as this med has the chances of increasing your blood sugar levels.

Side Effects

Some of the common side effects of using medrol are dizziness, drowsiness, head ache and excessive sweating. Severe side effects may happen in the patients and it is essential to get medical specialist help as soon as possible. Some of them are breathing troubles, increase in weight, change in menstrual cycle, chest pain, seizures, excessive hunger or thirst, mood swings, muscle pain, unusual skin sensation, change in vision and eye problems.

Tell the doctor if the patient experiences any allergic reaction within 12 minutes after halting the therapy.

Interaction with other drugs

It is found that Medrol interacts with certain kind of drugs. Hyaluronidase, Isoniazid, Amphotericin B, Lomitapide, Aprepitant, Leflunomide, ASA (acetylsalicylic acid) and macrolide antibiotics are a few among them. So to avoid these interactions tell to the medical practitioner about the prescription, non-prescription, over-the-counter, vitamins as well as herbal medications that are taken by the patient. Alcohol would increase the risk of drug interactions; hence avoid it during the course of therapy.


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