Phenergan also known as promethazine belongs to a class of drugs known as phenothiazine. This anti-anxiety drug works by affecting the chemical actions in the brain thereby changing the course of any allergy reactions in the body.

Phenergan works almost like an antihistamine since it also levels the severity of histamine, a chemical which occurs naturally in the body.

Some of the allergic symptoms treated by Phenergan include itchy skin rashes, runny nose, watery or itchy eyes, sneezing, hives and itching. Its use and significance after surgery cannot be ruled out since it prevents vomiting, motion sickness, pain, and can treat nausea. It is not used in treating respiratory conditions like pneumonia and asthma.


If you are planning to give the drug to a child less than 18 years of age, doctor’s advice is very essential. But it is strictly not advisable for children less than 2 years of age.

It is also important to get a prescription if you have any medical condition related to breathing, lungs, immunity, prostate, stomach, heart, liver, adrenal gland, blood pressure and bones.

The problems with prostate can be due to the increase in the size of gland or issues in passing urine and in the case of adrenal gland it can be because of the tumor that is termed as pheochromocytoma. When there are problems with the blood especially due to the minimum levels of calcium it is defined as hypocalcemia.

Studies are unclear on the possibility of the medication affecting an unborn baby, but on the safer side it is suggested to intimate the medical professional in advance if you are pregnant before taking this medication. Passing of active ingredients in the medication into breast milk is not completely ruled out and it is better to refrain from taking the medication while nursing a baby.

Dosage and Administration

It is very important to take Phenergan exactly in the way prescribed by the medico and completely adhere to all the directions mentioned in the prescription label. There exist possibilities where the medical professional may alter the dose levels in order to get the best outcomes. Similarly you should not take this medication in higher or lower amounts or for duration exceeding what has been prescribed.

Phenergan is commonly taken during the bedtime or before taking meals. For people afflicted with motion sickness, the drug should be taken at least 1hour before beginning the journey. Phenergan is normally given on the previous day night itself to patients undergoing surgery. The frequency and time of taking the drug is determined on the basis of the condition for which the drug is taken. The quantity of the liquid medicine needs to be measured with the assistance of the dosing syringe or by using a measuring spoon available specifically for dosages or even using a medicine cup. In the absence of the measuring device it is prudent to get one from the pharmacist.

In the event of a kid using the medication, convey the doctor if you notice any variation in the child’s weight. The dosage of Phenergan is dependent on the weight of the kids and any changes can have a bearing on the dose taken by the child.

Call the physician immediately if the symptoms do not get better or if they aggravate on taking Phenergan.

The dosage level varies on the basis of the ailment for which it is treated for.


The common dose is around 25 mg of the medication taken before going to bed and also you might take 12.5 before eating meals and while going to bed. It is normally sufficient if taken in single 25 mg dose before retiring or 6.25 mg to 12.5 mg taken thrice. On commencement of the treatment the dosage amount should be regulated to the minimum level possible just enough to relieve the symptoms.

Motion Sickness

The usual dose is 25mg of medication for the adults and has to be taken twice in a day. The first dose has to be taken before 30 minutes to 1 hour before the proposed journey.

Side Effects

The more common side effects are:

  • Dryness in the mouth
  • Dizziness
  • Problem with the vision where the objects appear as double
  • Nervous feeling
  • Weariness
  • Ringing sound in the ears throughout the day
  • The severe form of side effects includes:
  • High degree of drowsiness and feeling that the body is too frail
  • A sense of lightheadedness at times
  • Frequent instances of hallucinations leading to confusion
  • Experiencing seizures all of a sudden
  • Very fast or slow pulse rate
  • Being affected by jaundice
  • Unexplained reactions in the nervous system
  • Negative thoughts and a feeling of general disenchantment

On experiencing at least one of the above problems the medico needs to be immediately approached to get the desired relief.

Choosing between brand and generic variant of Phenergan

Phenergan is the brand medicine. There are a lot of generic medicines like Promethazine. You can make a choice in choosing brand or generic medicine. Both the drugs have the same chemical composition, except for a few inactive elements. Mostly, all generic medicines will have same output and side effects as brand medicine. To be on safer side, it is important to choose generic medicine from top manufacturers or stick with brand medicine.


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