Prednisolone is an immunosuppressant drug that is available as the generic formulation of Rayos. This drug is available in immediate-release, extended-release and in liquid form. It has a biological half-life of 18 to 16 hours.

What is Prednisolone prescribed for?

This synthetic Corticosteroid drug helps the patient in treating different conditions like Psoriasis, allergic disorders, arthritis, lupus, breathing problems (Asthma) as well as skin disorders and pain relief. It works by altering the response of the immune system to various diseases. This in turn decreases certain symptoms like swelling and allergic reactions.

Dosage and Administration

The dosage strengths available in immediate-release is 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg and 50 mg. In case of extended-release tablet, it is available in 1mg, 2 mg and 5 mg.

Prednisolone can be taken by mouth along with food or milk. This reduces the chance of stomach upset in the patient. Lots of water should be taken whilst administering the drug. Liquid form of this medication can be taken using a dose-measuring spoon. If a patient is prescribed with only one dose per day, it can be taken in the morning. Course duration is based on the patient’s response to the treatment as well as the severity of the problem.

The extended-release variant of prednisolone should not be crushed, chewed or broken. It should be taken as a whole to avoid drug overdose. It is very essential for a patient to perform blood tests and blood pressure checkups frequently during the treatment. Stopping pills should be done slowly and steadily. This helps an individual to avoid withdrawal symptoms as well as side effects.

Side effects

Just like other drugs, there are some side effects for this medication too. Restlessness, confusion, vomiting, head ache, nausea, skin rash, acne, trouble sleeping, weight gain are some of the most common side effects. There are certain ill effects that need to be monitored immediately by the medical practitioner and these symptoms are change in vision, depression, itching, sore throat, fever, cough, difficulty in urinating, seizures, sleep problems, dizziness and breathing troubles. As this drug would lower the potential of the immune system, patients would be more sensitive to infections. Avoid physical contact with a person who is affected with allergy, chicken pox or fever.

What drugs interact with Prednisolone?

Seizure medications, AIDS or HIV drugs, Digoxin, antifungal tablets, birth control pills, diabetes, Cyclosporine, Amphotericin B and tuberculosis medications are some of the drugs that interact with Prednisolone. If any such interactions happen, it would lead to unwanted ill effects. Avoid consumption of alcohol and tell to the physician if you are pregnant, nursing a baby or planning to become pregnant.


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