Triamterene is a diuretic, which is available as the generic formulation of Dyrenium. The route of administration of this drug is by mouth. The protein binding in this tablet is 67 % and has a half-life of one to two hours.

What is Triamterene prescribed for?

Triamterene is used in preventing the body from absorbing excessive salts as well as maintaining the level of potassium mainly caused by complications such as high blood pressure (hypertension). This is achieved by increasing the urination thus making the body to get rid of excessive salt as well as water. This in turn helps the kidney to get rid of excessive potassium and maintain the level of it.

Triamterene is also used in treating edema, nephrotic syndrome, cirrhosis of liver, as well as congestive heart failure. When the excessive water is reduced from the body, it in turn reduces fluid in the lungs and helps the patient to breathe easily.

Triamterene is often prescribed in combination with hydrochlorothiazide.

The efficacy of Triamterene in lessening the swelling of arms, abdomen or legs is also good.

Dosage and Administration

Triamterene medication is available in the dosage strengths of 50 mg and 100 mg. You have to consult with a health care professional and decide which dosage strength would be suitable for your medical condition. A doctor would instruct you to commence with smaller dosage strength then increase over a period of time.

Triamterene can be taken by mouth with a meal, as prescribed by the medical practitioner to prevent nausea or stomach upset. The pill is taken once or twice a day depending upon an individual’s illness.

To avoid urination during sleep, don not take Triamterene few hours before going to bed. Just like other pills, the dosage strength depends on the tolerance, response to the treatment as well as the severity of the problem.

In case of edema, the dose of Triamterene should not exceed 300 mg per day. When the patient is taking this pill to treat high blood pressure, the dose should not exceed 100 mg in a day.

As Triamterene would increase the level of potassium in the body, avoid taking potassium rich foods in a meal or any potassium tablets. It is essential not to stop the course of therapy abruptly as this would not only cause withdrawal of symptoms but also leads to ill effects. Consult the doctor and follow the instructions throughout the healing process.

Side effects of Triamterene

Numbness, weakness, breathing troubles, abnormal heart rate, confusion, tremors, restlessness, dizziness, light headed, nausea, loss of appetite, jaundice, head ache, dry mouth, vomiting and fever are some of the side effects that may be caused while using Triamterene.

Interaction with other drugs

There are certain drugs that could interact with Triamterene. Insulin or diabetes medicines, Lisinopril, Ramipril, Lithium, ACE inhibitors, Indomethacin, Aspirin, Diclofenac, Naproxen, Nabumetone, Etodolac and Piroxicam are a few among them.

They are chances for the ingredients in the drug to trigger allergy symptoms in you. Tell about the medications to the physician especially those bought with prescription, over-the-counter, herbal products as well as vitamin medications to your doctor in order to avoid interaction with Triamterene.


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