Zestril belongs to the class of drugs called as ACI inhibitors (angiotensin converting enzyme inhibitors). The generic version of this medication is lisinopril.  The inactive ingredients in this pill are red iron oxide, calcium hydrogen phosphate dehydrate, magnesium stearate, pregelatinized cornstarch, mannitol and cornstarch. The pink color pill is round in shape, biconvex and embossed with the number depending upon its dosage strength. 5 mg, 10 mg and 20 mg are the available dosage strength in the market.

Medical Uses

Zestril is used in treating individuals who are suffering from high blood pressure and heart failures. The pill is also taken after the person gets heart attack for avoiding the occurrence of the next attack. As this is an ACE inhibitor, it helps to widen the blood vessels, allowing more blood to flow to the heart. The blood pressure is reduced due to this action. It also enables the heart to function easily by reducing the work load.

Dosing Guide

Follow the instructions by the doctor on how to take Zestril throughout the treatment. It is taken by mouth with or without a meal. Dosage strength varies from a patient to another. It is very essential to take only the prescribed dose. Never increase or decrease the medication without physician’s advice. The drug is available in a syrup form. Measure the liquid form of the medication with a dose measuring spoon. It would avoid the chance of drug overdose. The dosage strength of the children is based on the weight hence have regular checkups on the weight and consult with the healthcare provider if there is any change in them.

Side Effects

It is found that the patients who are taking Zestril suffer from certain side effects. Some of the minor side effects are dizziness, depression, drowsiness, headache, vomiting, nausea, stomach upset, itching, cough and diarrhea. Some serious side effects may also be aggravated like psoriasis, weight gain, weakness, uneven heartbeats, chest pain, fever and flu like symptoms. In these cases, seek emergency medical assistance as soon as possible. History of angioedema, liver disease and diabetes are a few among them.

Interaction with other drugs

The patients should have knowledge about the drug interactions. This helps them to avoid taking those drugs together. Allopurinol, Amifostine, Antacids, Alpha agonists, Azathioprine, Rituximab, Sodium phosphates, and Sirolimus are some of them. Consult with the doctor on how to handle the drugs interactions. The physician would alter the dosage strength or may change the way the pill is being taken.


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